Rapid detection of ERG11 polymorphism associated azole resistance in Candida tropicalis.
Increasing reports of azole resistance in Candida tropicalis, highlight the development of rapid resistance detection techniques.Nonsynonymous mutations in the lanosterol C14 alpha-demethylase (ERG11) gene is one of the predominant mechanisms of azole resistance in C.tropicalis.We evaluated the tetra primer-amplification refractory mutation system-